Synthesis of 3/gb-acetoxy-24-norchola-5,20(22)-dien-23-al. a new intermediate for an improved synthesis of [24-14c]-cholesterol
[24-14C]-Cholesterol was synthesized by reaction between the phosphorane derivative of [1-14C]-isobutyltriphenylphosphonium bromide and 3β-acetoxy-24-norchola-5,20(22)-dien-23-al (IX) followed by hydrogenation of the condensation product. The intermediate IX was prepared by two different procedures...
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1973
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224731_v4_n2_p171_Colonna http://hdl.handle.net/20.500.12110/paper_00224731_v4_n2_p171_Colonna |
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Sumario: | [24-14C]-Cholesterol was synthesized by reaction between the phosphorane derivative of [1-14C]-isobutyltriphenylphosphonium bromide and 3β-acetoxy-24-norchola-5,20(22)-dien-23-al (IX) followed by hydrogenation of the condensation product. The intermediate IX was prepared by two different procedures both starting from pregnenolone acetate. © 1973. |
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