Tracheal remodelling in response to hypoxia
The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlle...
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00221910_v56_n5_p447_Centanin http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin |
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paper:paper_00221910_v56_n5_p447_Centanin2023-06-08T14:47:13Z Tracheal remodelling in response to hypoxia Centanin, Lázaro Wappner, Pablo Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved. Fil:Centanin, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Wappner, P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00221910_v56_n5_p447_Centanin http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda |
spellingShingle |
Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda Centanin, Lázaro Wappner, Pablo Tracheal remodelling in response to hypoxia |
topic_facet |
Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda |
description |
The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved. |
author |
Centanin, Lázaro Wappner, Pablo |
author_facet |
Centanin, Lázaro Wappner, Pablo |
author_sort |
Centanin, Lázaro |
title |
Tracheal remodelling in response to hypoxia |
title_short |
Tracheal remodelling in response to hypoxia |
title_full |
Tracheal remodelling in response to hypoxia |
title_fullStr |
Tracheal remodelling in response to hypoxia |
title_full_unstemmed |
Tracheal remodelling in response to hypoxia |
title_sort |
tracheal remodelling in response to hypoxia |
publishDate |
2010 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00221910_v56_n5_p447_Centanin http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin |
work_keys_str_mv |
AT centaninlazaro trachealremodellinginresponsetohypoxia AT wappnerpablo trachealremodellinginresponsetohypoxia |
_version_ |
1768542160464904192 |