Junín virus infection impairs stress-granule formation in Vero cells treated with arsenite via inhibition of eiF2α phosphorylation

Stress granules (SGs) are ephemeral cytoplasmic aggregates containing stalled translation preinitiation complexes involved in mRNA storage and triage during the cellular stress response. SG formation is triggered by the phosphorylation of the alpha subunit of eIF2 (eIF2α), which provokes a dramatic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Linero, Florencia N., Thomas, María Gabriela, Boccaccio, Graciela Lidia, Scolaro, Luis Alberto
Publicado: 2011
Materias:
arsenic trioxide
dithiothreitol
glycoprotein
initiation factor 2alpha
nucleoprotein
protein precursor
thapsigargin
arsenous acid derivative
initiation factor 2
messenger RNA
animal cell
Argentine hemorrhagic fever
article
cell granule
controlled study
Junin virus
nonhuman
priority journal
protein phosphorylation
Vero cell
American hemorrhagic fever
animal
Cercopithecus
drug antagonism
genetic transfection
genetics
metabolism
methodology
pathogenicity
phosphorylation
plasmid
Arenavirus
Animals
Arsenites
Cercopithecus aethiops
Cytoplasmic Granules
Eukaryotic Initiation Factor-2
Hemorrhagic Fever, American
Phosphorylation
Plasmids
RNA, Messenger
Transfection
Vero Cells
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00221317_v92_n12_p2889_Linero
http://hdl.handle.net/20.500.12110/paper_00221317_v92_n12_p2889_Linero
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares