Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation

Leukemia inhibitory factor (LIF) and oncostatin M (OSM) induce DNA synthesis in Swiss 3T3 cells through common signaling mechanism(s), whereas other related cytokines such as interleukin-6 and ciliary neurotrophic factor do not cause this response. Induction of DNA replication by LIF or prostaglandi...

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Detalles Bibliográficos
Autores principales:	Dekanty, Andrés, Sauane, Moira, Cadenas, María Belén, Barrio, María Marcela, Coso, Omar Adrian, Jiménez de Asúa, Luis A.F.
Publicado:	2006
Materias:	Leukemia Phosphorylation Translocation Biosynthesis Cells Cytology Diseases Enzyme inhibition DNA cyclin D cyclin D1 cyclin E leukemia inhibitory factor messenger RNA mitogen activated protein kinase 1 mitogen activated protein kinase 3 mitogen activated protein kinase kinase 1 STAT1 protein uo 126 cyclin G cycline cytokine interleukin 6 Lif protein, mouse mitogen activated protein kinase mitogen activated protein kinase kinase oncostatin M Osm protein, mouse prostaglandin F2 alpha protein kinase C protein tyrosine kinase retinoblastoma protein STAT protein animal cell animal tissue article cell cycle cell cycle S phase cell division cell strain 3T3 controlled study DNA replication DNA synthesis mitogenesis mouse nonhuman phosphorylation priority journal protein analysis protein expression protein function protein induction retinoblastoma signal transduction animal biosynthesis enzyme activation genetics kinetics metabolism physiology Animals Cyclin D1 Cyclins Cytokines Dinoprost DNA Replication Enzyme Activation Extracellular Signal-Regulated MAP Kinases Interleukin-6 Kinetics Leukemia Inhibitory Factor Mice Mitogen-Activated Protein Kinase Kinases Oncostatin M Protein Kinase C Protein-Tyrosine Kinases Retinoblastoma Protein S Phase Signal Transduction STAT Transcription Factors Swiss 3T3 Cells
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00219258_v281_n10_p6136_Dekanty http://hdl.handle.net/20.500.12110/paper_00219258_v281_n10_p6136_Dekanty
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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