Inhibition of aldosterone production in rat adrenal mitochondria by 18-ethynyl-11-deoxycorticosterone: A simple model for kinetic interpretation of mechanism-based inhibitors
A simple mathematical model for studying mechanism-based inhibitors (MBIs) is presented. The mathematical equations are deduced for an experimental protocol consisting of a first incubation of the enzyme in the presence of MBI followed by a washing protocol to eliminate free MBI. Finally enzyme acti...
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2001
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0021924X_v129_n3_p383_Matkovic http://hdl.handle.net/20.500.12110/paper_0021924X_v129_n3_p383_Matkovic |
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