Biological relevance of Hsp90-binding immunophilins in cancer development and treatment

Immunophilins are a family of intracellular receptors for immunosuppressive drugs. Those immunophilins that are related to immunosuppression are the smallest proteins of the family, i.e., FKBP12 and CyPA, whereas the other members of the family have higher molecular weight because the show additiona...

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Detalles Bibliográficos
Publicado:	2016
Materias:	FKBP38 FKBP51 FKBP52 FKBPL NF-κB steroid receptor 1 (3,3 dimethyl 1,2 dioxopentyl) 2 pyrrolidinecarboxylic acid 3 (3 pyridyl)propyl ester alm 201 bicalutamide calcineurin inhibitor calcium cisplatin cycloheximide cyclophilin 40 cyclophilin A etoposide fk 506 binding protein 12 fk 506 binding protein 38 fk 506 binding protein 51 fk 506 binding protein 52 glucocorticoid receptor heat shock protein 90 immunophilin methotrexate n (n',n' dimethylcarboxamidomethyl)cycloheximide paclitaxel rapamycin staurosporine tacrolimus unclassified drug amino acid sequence antineoplastic activity breast cancer cancer inhibition carcinogenesis colorectal carcinoma complex formation drug effect drug resistance glioma human lymphoma melanoma neoplasm nonhuman pancreas cancer priority journal prostate cancer protein protein interaction Review signal transduction animal metabolism Animals HSP90 Heat-Shock Proteins Humans Immunophilins Neoplasms
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00207136_v138_n4_p797_Mazaira http://hdl.handle.net/20.500.12110/paper_00207136_v138_n4_p797_Mazaira
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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