Studies on the active centre(s) of rat liver porphyrinogen carboxy-lyase. in vivo effect of hexachlorobenzene on decarboxylation site(s) of porphyrinogens

1. 1. The role of histidine on the decarboxylation of porphyrinogens of 7-, 6-, and 5-COOH III brought about by porphyrinogen carboxy-lyase (PCL) was studied. 2. 2. For this purpose hepatic PCL from normal and hexachlorobenzene (HCB) treated rats were modified with diethylpyrocarbonate. 3. 3. The re...

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Detalles Bibliográficos
Publicado: 1994
Materias:
hexachlorobenzene
porphyrinogen
uroporphyrinogen decarboxylase
animal experiment
animal model
article
binding site
carboxy terminal sequence
decarboxylation
drug effect
enzyme active site
enzyme binding
enzyme modification
female
nonhuman
porphyria
rat
Animal
Arginine
Binding Sites
Carboxy-Lyases
Decarboxylation
Diacetyl
Female
Hexachlorobenzene
Histidine
Liver
Porphyria
Porphyrinogens
Rats
Rats, Wistar
Support, Non-U.S. Gov't
Animalia
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020711X_v26_n4_p595_deCatabbi
http://hdl.handle.net/20.500.12110/paper_0020711X_v26_n4_p595_deCatabbi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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