A unique family of stable and water-soluble S-nitrosothiol complexes
In this work, we present a complete and detailed experimental characterization and theoretical study of a variety of coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenyl thiol. Some of them are extremely unstable and sensitive in free for...
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2008
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00201669_v47_n11_p4723_Perissinotti http://hdl.handle.net/20.500.12110/paper_00201669_v47_n11_p4723_Perissinotti |
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paper:paper_00201669_v47_n11_p4723_Perissinotti2023-06-08T14:40:35Z A unique family of stable and water-soluble S-nitrosothiol complexes Perissinotti, Laura L. Estrin, Dario Ariel Doctorovich, Fabio Ariel 2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water In this work, we present a complete and detailed experimental characterization and theoretical study of a variety of coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenyl thiol. Some of them are extremely unstable and sensitive in free form. Strikingly, in contrast with free S-nitrosothiols, we found that, upon coordination to iridium, they become very stable even in aqueous solutions. The study of these coordinated complexes provides further insight on the elucidation of structural aspects dealing with the nature of the S-N bond in RSNOs, a fact which still remains a matter of controversy. © 2008 American Chemical Society. Fil:Perissinotti, L.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Estrin, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Doctorovich, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00201669_v47_n11_p4723_Perissinotti http://hdl.handle.net/20.500.12110/paper_00201669_v47_n11_p4723_Perissinotti |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water |
spellingShingle |
2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water Perissinotti, Laura L. Estrin, Dario Ariel Doctorovich, Fabio Ariel A unique family of stable and water-soluble S-nitrosothiol complexes |
topic_facet |
2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water |
description |
In this work, we present a complete and detailed experimental characterization and theoretical study of a variety of coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenyl thiol. Some of them are extremely unstable and sensitive in free form. Strikingly, in contrast with free S-nitrosothiols, we found that, upon coordination to iridium, they become very stable even in aqueous solutions. The study of these coordinated complexes provides further insight on the elucidation of structural aspects dealing with the nature of the S-N bond in RSNOs, a fact which still remains a matter of controversy. © 2008 American Chemical Society. |
author |
Perissinotti, Laura L. Estrin, Dario Ariel Doctorovich, Fabio Ariel |
author_facet |
Perissinotti, Laura L. Estrin, Dario Ariel Doctorovich, Fabio Ariel |
author_sort |
Perissinotti, Laura L. |
title |
A unique family of stable and water-soluble S-nitrosothiol complexes |
title_short |
A unique family of stable and water-soluble S-nitrosothiol complexes |
title_full |
A unique family of stable and water-soluble S-nitrosothiol complexes |
title_fullStr |
A unique family of stable and water-soluble S-nitrosothiol complexes |
title_full_unstemmed |
A unique family of stable and water-soluble S-nitrosothiol complexes |
title_sort |
unique family of stable and water-soluble s-nitrosothiol complexes |
publishDate |
2008 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00201669_v47_n11_p4723_Perissinotti http://hdl.handle.net/20.500.12110/paper_00201669_v47_n11_p4723_Perissinotti |
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1768541689007308800 |