Synthesis of (2′s)-2′-deoxy-2′-C-methylpurine nucleosides and their phosphoramidites
We describe the stereoselective synthesis of (2′S)-2′-deoxy-2′-C-methyladenosine (12) and (2′S)-2′-deoxy-2′-C-methylinosine (14) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-0-(2,6-dichlorophenyl)inosine as starting material. The methyl group at the 2′-position was int...
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| Publicado: |
2002
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0018019X_v85_n5_p1284_Caballero http://hdl.handle.net/20.500.12110/paper_0018019X_v85_n5_p1284_Caballero |
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