R-Spondin3 is associated with basal-progenitor behavior in normal and tumor mammary cells

R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role of RSPO3 in mammary gland and breast cancer development remains unclear. In this study, we show that RSPO3 is expressed in the basal stem cell...

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Detalles Bibliográficos
Publicado: 2018
Materias:
G protein coupled receptor
leucine rich repeat containing G protein coupled receptor
protein
R spondin3
transcription factor RUNX
unclassified drug
adult
animal cell
animal experiment
animal model
animal tissue
Article
basal like breast cancer
breast carcinogenesis
breast cell
cancer cell
cancer growth
cell differentiation
cell migration
controlled study
epithelial mesenchymal transition
female
gene
gene knockdown
gene overexpression
gene targeting
human
human cell
human tissue
in vivo study
mouse
nonhuman
priority journal
protein expression
RSPO3 gene
stem cell
Wnt signaling
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00085472_v78_n16_p4497_Tocci
http://hdl.handle.net/20.500.12110/paper_00085472_v78_n16_p4497_Tocci
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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