Histamine H2 receptor overexpression induces U937 cell differentiation despite triggered mechanisms to attenuate cAMP signalling

Knowing that cell-surface receptors that recognize and respond to extracellular stimuli are key components for the regular communication between individual cells required for the survival of any living organism, the aim of the present work was to investigate the effect of H2R overexpression on the U...

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Detalles Bibliográficos
Autores principales:	Fernández, Natalia C., Mladovan, Alejandro G., Shayo, Carina C.
Publicado:	2006
Materias:	cAMP Cell differentiation GRK Histamine receptors PDE Receptor overexpression amthamine cyclic AMP G protein coupled receptor kinase 2 histamine H2 receptor histamine H2 receptor agonist phosphodiesterase rolipram article cell differentiation cell proliferation concentration response controlled study desensitization enzyme activity gene overexpression human human cell priority journal signal transduction Calcium Cell Differentiation Cyclic AMP Dose-Response Relationship, Drug Histamine Agonists Humans Phosphoric Diester Hydrolases Radioligand Assay Receptors, G-Protein-Coupled Receptors, Histamine H2 Signal Transduction U937 Cells
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00062952_v71_n8_p1219_Monczor http://hdl.handle.net/20.500.12110/paper_00062952_v71_n8_p1219_Monczor
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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