Effect of in vivo administered hexachlorobenzene on epidermal growth factor receptor levels, protein tyrosine kinase activity, and phosphotyrosine content in rat liver

In the present study, the effects of hexachlorobenzene (HCB) on epidermal growth factor receptor (EGFR) content of liver microsomes and plasma membrane, and on EGFR-tyrosine kinase activity in the microsomal fraction were investigated. In addition, we studied the parameters of the tyrosine kinase si...

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Detalles Bibliográficos
Autores principales:	Randi, Andrea Silvana, Sancovich, Horacio Alberto, Ferramola, Ana María, Spinelli, María Fernanda, Kleiman de Pisarev, Diana L.
Publicado:	2003
Materias:	EGFR kinase activity EGFR levels Hexachlorobenzene Phosphotyrosine content Protein tyrosine kinase Rat liver epidermal growth factor receptor hexachlorobenzene phosphotyrosine protein tyrosine kinase animal cell article cell membrane controlled study cytosol enzyme activity enzyme inhibition female liver liver cell liver microsome nonhuman priority journal protein phosphorylation rat reduction signal transduction toxicity
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00062952_v65_n9_p1495_Randi http://hdl.handle.net/20.500.12110/paper_00062952_v65_n9_p1495_Randi
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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