Protein synthesis and ribosomal distribution in a polyamine auxotroph of Escherichia coli: Studies in cell-free systems

Phenylalanine incorporation into polypeptides induced by poly (U) is markedly reduced in extracts obtained from polyamine depleted bacteria, and this effect, totally independent of RNA synthesis, is related to some deficiency at the level of the ribosomal particles and/or the factors bound to them....

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Autor principal: Algranati, Israel David
Publicado: 1975
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v62_n2_p313_Echandi
http://hdl.handle.net/20.500.12110/paper_0006291X_v62_n2_p313_Echandi
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Sumario:Phenylalanine incorporation into polypeptides induced by poly (U) is markedly reduced in extracts obtained from polyamine depleted bacteria, and this effect, totally independent of RNA synthesis, is related to some deficiency at the level of the ribosomal particles and/or the factors bound to them. The ribosomal profiles corresponding to polyamine starved cells change when cultures are supplemented with putrescine. © 1975 Academic Press, Inc.