Evidence that protein kinase C is involved in δ-aminolevulinate synthase expression in rat hepatocytes

There are many factors that regulate the rate of synthesis of δ- aminolevulinate synthase (ALA-S), the enzyme which governs the rate-limiting step in heme biosynthesis. In rat hepatocytes, phenobarbital increases ALA-S gene transcription and dibutyryl cAMP potentiates this induction, whereas insulin...

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Detalles Bibliográficos
Autores principales:	Varone, Cecilia Laura, Cánepa, Eduardo Tomás
Publicado:	1997
Materias:	aminolevulinic acid synthase cAMP diacylglycerol gene expression hepatocytes phorbol esters protein kinase C 5 aminolevulinate synthase bucladesine cyclic AMP dioctanoin glucose heme insulin messenger RNA phenobarbital phorbol 13 acetate 12 myristate animal cell article controlled study enzyme activation gene expression regulation liver cell male nonhuman priority journal protein expression rat transcription regulation Animalia Canis familiaris
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00039861_v341_n2_p259_Varone http://hdl.handle.net/20.500.12110/paper_00039861_v341_n2_p259_Varone
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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