Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections

<p The efficacy and tolerance of levofloxacin for the treatment of skin and urinary tract infections were evaluated in canines. Twenty six clinical cases were included and treated orally with 10 mg/kg every 24 hours for 14 to 21 days. From the 14 cases of skin disorders, 4 corresponded to sev...

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Autores principales: Casas, L, Vaz, S, Landoni, M F.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2019
Materias:
Canine
levofloxacin
efficacy
dermatitis
urinary tract infection
Canino
levofloxacina
eficacia
infección urinaria
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/3892
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-3892
record_format ojs
spelling I48-R154-article-38922025-02-12T21:58:55Z Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections Eficacia clínica de levofloxacina en el tratamiento de caninos con procesos infecciosos cutáneos y urinarios Casas, L Vaz, S Landoni, M F. Canine levofloxacin efficacy dermatitis urinary tract infection Canino levofloxacina eficacia dermatitis infección urinaria <p The efficacy and tolerance of levofloxacin for the treatment of skin and urinary tract infections were evaluated in canines. Twenty six clinical cases were included and treated orally with 10 mg/kg every 24 hours for 14 to 21 days. From the 14 cases of skin disorders, 4 corresponded to severe cases and the rest to intermediate severity. From the 12 cases of infections at urinary level, 8 corresponded to severe infections, 3 were intermediate and one was low. Treatment was successful in 99% of the cases of dermatitis. Clinical cure (score 0) was observed at day 4 for 6.25% and day 7 for 43.75% of the animals, respectively. By day 14 clinical cure was observed in 99% of patients. One patient required a 21-day treatment to reach score 0. In the population with urinary infections, all patients responded satisfactorily to treatment (clinical cure-score 0), 42% on day 4 and 83% on day 7. By day 14 clinical cure was observed in 100% of patients. No side effects were observed in any of the patients included in the study. Levofloxacin (Floxaday®, Holliday-Scott) administered orally at a dose of 10 mg/kg once a day in canines, demonstrated excellent efficacy with no adverse effects.p>  La eficacia y tolerancia de levofloxacina (Floxaday®, Holliday-Scott) para el tratamiento de infecciones dérmicas y de vías urinarias, fue evaluada en caninos. Se incluyeron 26 casos clínicos que fueron tratados con 10 mg/kg vía oral cada 24 horas durante 14 y hasta 21 días. De los 14 casos de afecciones a nivel dérmico, 4 fueron severos y los restantes de severidad intermedia. De los 12 casos de infecciones a nivel urinario, 8 fueron procesos severos, 3 intermedios y uno bajo. La eficacia de los tratamientos fue evaluada aplicando una escala ad-hoc. El tratamiento fue exitoso en el 99% de los casos, observándose curación clínica al día 4 en el 6,25% y al día 7 en el 43,75%. En el día 14 la curación clínica fue registrada en el 99% de los pacientes; solamente uno de ellos requirió un tratamiento de 21 días para alcanzarla. En la población con infecciones urinarias todos los pacientes respondieron satisfactoriamente al tratamiento (curación clínica), el 42% lo hizo hacia el día 4 y el 83% al día 7. Al día 14, la curación clínica fue constatada en el 100% de los casos. No se observaron efectos secundarios en ninguno de los pacientes incluidos en el estudio. En caninos, levofloxacina administrada por vía oral a la dosis de 10 mg/kg una vez al día, demostró una excelente eficacia y nula aparición de efectos adversos.  Universidad Nacional del Nordeste 2019-08-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/3892 10.30972/vet.3013892 Revista Veterinaria; Vol. 30 Núm. 1 (2019); 17-22 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/3892/3513 Derechos de autor 2019 L Casas, S Vaz, M F. Landoni https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
topic Canine
levofloxacin
efficacy
dermatitis
urinary tract infection
Canino
levofloxacina
eficacia
dermatitis
infección urinaria
spellingShingle Canine
levofloxacin
efficacy
dermatitis
urinary tract infection
Canino
levofloxacina
eficacia
dermatitis
infección urinaria
Casas, L
Vaz, S
Landoni, M F.
Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
topic_facet Canine
levofloxacin
efficacy
dermatitis
urinary tract infection
Canino
levofloxacina
eficacia
dermatitis
infección urinaria
author Casas, L
Vaz, S
Landoni, M F.
author_facet Casas, L
Vaz, S
Landoni, M F.
author_sort Casas, L
title Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
title_short Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
title_full Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
title_fullStr Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
title_full_unstemmed Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
title_sort clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections
description <p The efficacy and tolerance of levofloxacin for the treatment of skin and urinary tract infections were evaluated in canines. Twenty six clinical cases were included and treated orally with 10 mg/kg every 24 hours for 14 to 21 days. From the 14 cases of skin disorders, 4 corresponded to severe cases and the rest to intermediate severity. From the 12 cases of infections at urinary level, 8 corresponded to severe infections, 3 were intermediate and one was low. Treatment was successful in 99% of the cases of dermatitis. Clinical cure (score 0) was observed at day 4 for 6.25% and day 7 for 43.75% of the animals, respectively. By day 14 clinical cure was observed in 99% of patients. One patient required a 21-day treatment to reach score 0. In the population with urinary infections, all patients responded satisfactorily to treatment (clinical cure-score 0), 42% on day 4 and 83% on day 7. By day 14 clinical cure was observed in 100% of patients. No side effects were observed in any of the patients included in the study. Levofloxacin (Floxaday®, Holliday-Scott) administered orally at a dose of 10 mg/kg once a day in canines, demonstrated excellent efficacy with no adverse effects.p> 
publisher Universidad Nacional del Nordeste
publishDate 2019
url https://revistas.unne.edu.ar/index.php/vet/article/view/3892
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last_indexed 2025-05-17T05:09:44Z
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