Características de los venenos de escorpiones

A scorpion uses its venom to capture its prey, or as a defense system when it feels threatened. This substance is an apocrine secretion, which is violently ejected by the stinger located in the metasoma of the scorpion, which a lso houses the glands responsible for producing it and a holl...

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Detalles Bibliográficos
Autores principales: Rincón Cortés, Clara Andrea, Landaeta Valero, Eliana Maritza, Rodríguez Ríos, Lina María
Formato: Working Paper
Lenguaje:Español
Publicado: Universidad de Belgrano. Red Latinoamericana de Cooperación Universitaria. RLCU 2013
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Acceso en línea:http://repositorio.ub.edu.ar/handle/123456789/1953
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Sumario:A scorpion uses its venom to capture its prey, or as a defense system when it feels threatened. This substance is an apocrine secretion, which is violently ejected by the stinger located in the metasoma of the scorpion, which a lso houses the glands responsible for producing it and a hollow spine which provides its venom. As for the composition, the venom has about 80 toxins, characterized by being low molecular weight peptides that recognize ion channels and modify the cellular excitability that may or may not cause toxicity in mammals. Some peptides characterized from scorpion venoms have been classified into three groups: short-chain neurotoxins from 30 to 40 amino acids, medium chain from 60 to 70 amino acids and long chain. Medium-chain neurotoxins are those with greater medical importance because they affect mammals, distinguishing two classes, alpha and beta, according to their pharmacological function of Na + channels. The alpha type have been isolated from the venom of scorpions of the Middle East and North Africa and the beta-type scorpion in North and South America. There are also peptides that are harmless to mammals, but are harmful to crustaceans, spiders and insects, for example the AHIT1 excitatory toxins, BjTl1 y Lqq Tl1, which produce paralysis on the Sarcophaga falculatelarva. Thus demonstrated that scorpion toxins are selective for insects and may be candidates for the preparation of various biological control products.