Impairment of CFTR activity in cultured epithelial cells upregulates the expression and activity of LDH resulting in lactic acid hypersecretion

Asbtract: Mutations in the gene encoding the CFTR chloride channel produce cystic fibrosis (CF). CF patients are more susceptible to bacterial infections in lungs. The most accepted hypothesis sustains that a reduction in the airway surface liquid (ASL) volume favor infections. Alternatively, it was...

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Autores principales: Valdivieso, Ángel Gabriel, Clauzure, Mariángeles, Massip Copiz, María Macarena, Cancio, Carla E., Asensio, Cristian, Mori, Consuelo, Santa Coloma, Tomás Antonio
Formato: Artículo
Lenguaje:Inglés
Publicado: Springer 2020
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/9596
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