Disruption of interleukin-1 β autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function
Abstract: Patients with cystic fibrosis (CF) have elevated concentration of cytokines in sputum and a general inflammatory condition. In addition, CF cells in culture produce diverse cytokines in excess, including IL-1b. We have previously shown that IL-1b, at low doses (,30 pM), can stimulate the e...
Guardado en:
| Autores principales: | Clauzure, Mariángeles, Valdivieso, Ángel Gabriel, Massip Copiz, María Macarena, Schulman, Gustavo, Teiber, María Luz, Santa Coloma, Tomás Antonio |
|---|---|
| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Dominik Hartl, University of Tübingen, Germany
2019
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| Materias: | |
| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/8675 |
| Aporte de: |
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