Lysophosphatidic acid-activated calcium signaling is elevated in red cells from sickle cell disease patients

Abstract: (1) Background: It is known that sickle cells contain a higher amount of Ca2+ compared to healthy red blood cells (RBCs). The increased Ca2+ is associated with the most severe symptom of sickle cell disease (SCD), the vaso-occlusive crisis (VOC). The Ca2+ entry pathway received the name...

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Autores principales: Wang, Jue, Hertz, Laura, Ruppenthal, Sandra, El Nemer, Wassim, Connes, Philippe, Goede, Jeroen S., Bogdanova, Anna, Birnbaumer, Lutz, Kaestner, Lars
Formato: Artículo
Lenguaje:Inglés
Publicado: MDPI 2021
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/11619
https://doi.org/10.3390/cells10020456
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