Perturbation of Chromatin Structure Globally Affects Localization and Recruitment of Splicing Factors

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Chromatin structure is an important factor in the functional coupling between transcription and mRNA processing, not only by regulating alternative splicing events, but also by contributing to exon recognition during constitutive splicing. We observed that depolarization of neuroblastoma cell membra...

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Detalles Bibliográficos
Autores principales: Schor, I.E., Llères, D., Risso, G.J., Pawellek, A., Ule, J., Lamond, A.I., Kornblihtt, A.R.
Formato: Artículo publishedVersion
Publicado: 2012
Materias:
enhanced green fluorescent protein
heterochromatin protein 1
heterochromatin protein 1alpha
histone H3
histone H4
messenger RNA
nuclear protein
protein SRSF1
protein SRSF2
trichostatin A
unclassified drug
untranslated RNA
article
bioaccumulation
cell nucleus
cellular distribution
chromatin structure
controlled study
gene control
gene function
histone acetylation
human
human cell
MALAT1 gene
molecular imaging
molecular model
NCAM gene
Neat1 gene
protein determination
protein function
protein RNA binding
regulatory mechanism
RNA analysis
RNA gene
RNA splicing
spliceosome
structure analysis
Acetylation
Alternative Splicing
Animals
Cell Line
Cell Nucleus
Chromatin
Histones
Humans
Hydroxamic Acids
Membrane Potentials
Models, Biological
Protein Binding
Protein Transport
Ribonucleoproteins
RNA Precursors
RNA Splice Sites
RNA Splicing
RNA, Long Untranslated
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v7_n11_p_Schor
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_19326203_v7_n11_p_Schor_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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