Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease

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Background: Alzheimer's disease (AD) is characterized by a neurodegenerative progression that alters cognition. On a phenotypical level, cognition is evaluated by means of the MiniMental State Examination (MMSE) and the post-morten examination of Neurofibrillary Tangle count (NFT) helps to conf...

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Detalles Bibliográficos
Autores principales: Gómez Ravetti, M., Rosso, O.A., Berretta, R., Moscato, P.
Formato: Artículo publishedVersion
Publicado: 2010
Materias:
biological marker
calcium
early growth response factor
epidermal growth factor receptor
insulin
Myc associated zinc finger protein
phosphatidylinositol
transcription factor
transcription factor E2F1
unclassified drug
Wnt protein
zinc finger protein
Alzheimer disease
article
bioinformatics
calcium signaling
clinical article
cognitive defect
controlled study
disease course
disease severity
gene expression profiling
gene expression regulation
gene probe
hippocampus
human
human tissue
information science
microarray analysis
mini mental state examination
nerve cell plasticity
neurofibrillary tangle
neurofilament
sequence homology
signal transduction
Alzheimer Disease
Biological Markers
Cognition Disorders
Computational Biology
Gene Expression Profiling
Hippocampus
Humans
Neuronal Plasticity
Oligonucleotide Array Sequence Analysis
Transcription Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v5_n4_p_GomezRavetti
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_19326203_v5_n4_p_GomezRavetti_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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