Relative contribution of V-H+ATPase and NA+/ H+ exchanger to bicarbonate reabsorption in proximal convoluted tubules of old rats

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With aging, the kidney develops a progressive deterioration of several structures and functions. Proximal tubular acidification is impaired in old rats with a decrease in the activity of brush border Na+/ H+ exchange and a fall of H-ion flux measured with micropuncture experiments. In the present wo...

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Detalles Bibliográficos
Autores principales: Fiori, M., Radrizzani, M., Díaz-sylvester, P., Müller, A., Corti, T., Monserrat, A., Amorena, C.
Formato: Artículo publishedVersion
Publicado: 2006
Materias:
Aging
Kidney
Micropuncture experiments
Na+/H+ exchange
V-H+-ATPase
Western blot
amiloride derivative
bafilomycin
bicarbonate
isoprotein
protein antibody
proton transporting adenosine triphosphatase
sodium proton exchange protein
sodium proton exchange protein 3
aged
animal cell
animal experiment
animal model
animal tissue
article
cell isolation
controlled study
in vitro study
kidney acidifying capacity
kidney proximal tubule
membrane vesicle
nonhuman
priority journal
punch biopsy
rat
Western blotting
Amiloride
Animals
Bicarbonates
Blotting, Western
Hydrogen-Ion Concentration
Kidney Tubules, Proximal
Microvilli
Rats
Sodium Channel Blockers
Sodium-Hydrogen Antiporter
Vacuolar Proton-Translocating ATPases
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14749718_v5_n5_p367_Fiori
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_14749718_v5_n5_p367_Fiori_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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