Interference in dengue virus adsorption and uncoating by carrageenans

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This study demonstrated that the λ- and ι-carrageenans, sulfated polysaccharides containing linear chains of galactopyranosyl residues, are potent inhibitors of dengue virus type 2 (DENV-2) and 3 (DENV-3) multiplication in Vero and HepG2 cells, with values of effective concentration 50% from 0.14 to...

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Detalles Bibliográficos
Autores principales: Talarico, L.B., Damonte, E.B.
Formato: Artículo publishedVersion
Publicado: 2007
Materias:
Adsorption
Carrageenan
Dengue virus
Flavivirus
Heparan sulfate
Internalization
Uncoating
Virus entry
antivirus agent
carrageenan
coat protein
heparan sulfate
animal cell
antigen expression
antiviral activity
article
controlled study
dengue
dose response
dose time effect relation
drug inhibition
drug structure
endosome
host cell
human
human cell
internalization
macromolecule
nonhuman
priority journal
protein synthesis
reverse transcription polymerase chain reaction
virion
virogenesis
virus adsorption
virus inhibition
virus nucleocapsid
Animals
Cell Line
Dengue
Dengue Virus
Dose-Response Relationship, Drug
Humans
Virus Replication
Dengue virus type 2
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00426822_v363_n2_p473_Talarico
http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_00426822_v363_n2_p473_Talarico_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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