Intrabursal administration of the antiangiopoietin 1 antibody produces a delay in rat follicular development associated with an increase in ovarian apoptosis mediated by changes in the expression of BCL2 related genes

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The angiopoietin (ANGPT) receptor (TEK) system plays a crucial role in blood vessel development and regression. To date, no reports have addressed the actions of the anti-ANGPT1 antibody on gonadotropin-stimulated follicular development and atresia in the ovary. Therefore, in this study we specifica...

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Autores principales:	Parborell, F., Abramovich, D., Tesone, M.
Formato:	Artículo publishedVersion
Publicado:	2008
Materias:	Angiogenesis Angiopoietin 1 Apoptosis Follicle Ovary angiopoietin 1 angiopoietin 1 antibody Fas antigen Fas ligand gonadotropin inhibitor of apoptosis protein protein antibody protein Bax protein bcl 2 protein bcl x unclassified drug angiogenesis animal cell animal experiment animal model apoptosis article cell culture controlled study culture medium DNA fragmentation gene expression granulosa cell nonhuman ovary ovary follicle ovary follicle atresia ovary follicle development paracrine signaling prepuberty priority journal protein blood level protein expression protein family protein function rat theca cell Angiopoietin-1 Animals Antibodies Cell Count DNA Fragmentation Endothelium Female Gene Expression Regulation, Developmental Gonadotropins Injections, Intraperitoneal Ovarian Follicle Peritoneal Cavity Proto-Oncogene Proteins c-bcl-2 Rats Rats, Sprague-Dawley Sexual Maturation Rattus
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00063363_v78_n3_p506_Parborell https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_00063363_v78_n3_p506_Parborell_oai
Aporte de:	Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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