Micobacterium intracellulare en paciente con síndrome de Lady Windermere
Mycobacterium intracellulare is a non-tuberculous acid-alcohol resistant bacillus, which belongs to the complex Mycobacterium avium. The infection due to M. intracellulare can manifest itself as a fibrocavitary lung disease, as a hypersensitivity pneumonitis, or as a bronchiectasis superinfection, o...
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| Autores principales: | , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Facultad de Bioquímica y Ciencias Biológicas (UNL)
2022
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| Acceso en línea: | https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FABICIB/article/view/12268 |
| Aporte de: |
| Sumario: | Mycobacterium intracellulare is a non-tuberculous acid-alcohol resistant bacillus, which belongs to the complex Mycobacterium avium. The infection due to M. intracellulare can manifest itself as a fibrocavitary lung disease, as a hypersensitivity pneumonitis, or as a bronchiectasis superinfection, one of which variants is the Lady Windermere syndrome (LWS), affecting slender elderly women, with higher incidence of scoliosis, and with bronchiectasis and/or nodules in the middle lobe or lingula. A case of a 61-year-old female patient is reported –with a diagnosis of COPD, extreme thinness, and scoliosis–, who consults due to a respiratory syndrome of cough with expectoration, general malaise, fever and tiredness. The tomography shows evidence of bronchiectasis and nodules in the middle lobe and lingula. A sputum culture is ordered for mycobacteria and bacilloscopy. The results were ZN ++++ and culture positive. A molecular identification was conducted at the Instituto Malbrán. Isolation showed a 100% identity with the pattern strain of Mycobacterium intracellulare ATCC 13950. Knowing whether a lung disease caused by environmental mycobacteria –such as LWS– exists would allow an earlier diagnosis, avoiding the clinical deterioration of the patient, and a lower charge on the resources of medical attention during long periods of time. |
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