Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)

The high incidence of diarrhea in the population demands a search for new therapeutic options and easy access, mainly from plant-based sources. Leaves and bark of Guazuma ulmifolia Lam. (Sterculiaceae) are popularly employed against diarrhea. However, no information was found in the literature about...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Michelin, Daniele C., Almeida, Glalber C. de, Galina, Karen Janaina, Lopes, Gisely C., Nakamura, Celso Vataru, Dias Filho, Benedito Prado, Ueda Nakamura, Tânia, Salgado, Hérida R.N., Mello, João Carlos Palazzo de
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia antidiarrheal activity; antimicrobial screening; condensed tannins; Guazuma ulmifolia; sterculiaceae Farmacología Plantas medicinales Evaluación de drogas Extractos de plantas Enfermedades gastrointestinales
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8021 http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_6.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8021
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia antidiarrheal activity; antimicrobial screening; condensed tannins; Guazuma ulmifolia; sterculiaceae Farmacología Plantas medicinales Evaluación de drogas Extractos de plantas Enfermedades gastrointestinales
spellingShingle	Farmacia antidiarrheal activity; antimicrobial screening; condensed tannins; Guazuma ulmifolia; sterculiaceae Farmacología Plantas medicinales Evaluación de drogas Extractos de plantas Enfermedades gastrointestinales Michelin, Daniele C. Almeida, Glalber C. de Galina, Karen Janaina Lopes, Gisely C. Nakamura, Celso Vataru Dias Filho, Benedito Prado Ueda Nakamura, Tânia Salgado, Hérida R.N. Mello, João Carlos Palazzo de Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)
topic_facet	Farmacia antidiarrheal activity; antimicrobial screening; condensed tannins; Guazuma ulmifolia; sterculiaceae Farmacología Plantas medicinales Evaluación de drogas Extractos de plantas Enfermedades gastrointestinales
description	The high incidence of diarrhea in the population demands a search for new therapeutic options and easy access, mainly from plant-based sources. Leaves and bark of Guazuma ulmifolia Lam. (Sterculiaceae) are popularly employed against diarrhea. However, no information was found in the literature about this supposed property of the drug. In this study we evaluated in vivo antidiarrheal activity of stem bark extracts from G. ulmifolia in mice, and in vitro antimicrobial activity against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Salmonella sp., Shigella flexneri, and Pseudomonas aeruginosa by using the microdilution method. The n-BuOH semipurified fraction (GU#3) significantly reduced intestinal motility. The extracts did not show antimicrobial activity. G. ulmifolia Lam. had non-specific antidiarrheal, and antimotility activity in the experimental models studied, and could be used as an alternative treatment for non-infectious diarrhea.
format	Articulo Comunicacion
author	Michelin, Daniele C. Almeida, Glalber C. de Galina, Karen Janaina Lopes, Gisely C. Nakamura, Celso Vataru Dias Filho, Benedito Prado Ueda Nakamura, Tânia Salgado, Hérida R.N. Mello, João Carlos Palazzo de
author_facet	Michelin, Daniele C. Almeida, Glalber C. de Galina, Karen Janaina Lopes, Gisely C. Nakamura, Celso Vataru Dias Filho, Benedito Prado Ueda Nakamura, Tânia Salgado, Hérida R.N. Mello, João Carlos Palazzo de
author_sort	Michelin, Daniele C.
title	Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)
title_short	Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)
title_full	Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)
title_fullStr	Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)
title_full_unstemmed	Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)
title_sort	antidiarrheal activity of <i>guazuma ulmifolia</i> lam. (sterculiaceae)
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/8021 http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_6.pdf
work_keys_str_mv	AT michelindanielec antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT almeidaglalbercde antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT galinakarenjanaina antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT lopesgiselyc antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT nakamuracelsovataru antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT diasfilhobeneditoprado antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT uedanakamuratania antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT salgadoheridarn antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae AT mellojoaocarlospalazzode antidiarrhealactivityofiguazumaulmifoliailamsterculiaceae
bdutipo_str	Repositorios
_version_	1764820486677594116

Antidiarrheal activity of <i>Guazuma ulmifolia</i> Lam. (Sterculiaceae)

Ejemplares similares