Metallo-β-lactamase inhibitors inspired on snapshots from the catalytic mechanism

β-Lactam antibiotics are the most widely prescribed antibacterial drugs due to their low toxicity and broad spectrum. Their action is counteracted by different resistance mechanisms developed by bacteria. Among them, the most common strategy is the expression of β-lactamases, enzymes that hydroly...

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Detalles Bibliográficos
Autores principales:	Palacios, Antonela R., Rossi, María Agustina, Mahler, Graciela S., Vila, Alejandro J.
Formato:	article artículo publishedVersion
Lenguaje:	Inglés
Publicado:	MDPI 2021
Materias:	Metallo-beta-lactamases Mechanism-based Inhibitors Drug Resistance, Microbial Reaction Mechanism
Acceso en línea:	http://hdl.handle.net/2133/20476 http://hdl.handle.net/2133/20476
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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