The Ca2+-calmodulin-Ca2+/calmodulin-dependent protein kinase II pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in rat hepatocytes

Oxidative stress is a common event in most hepatopathies, leading to mitochondrial permeability transition pore (MPTP) formation and further exacerbation of both oxidative stress from mitochondrial origin and cell death. Intracellular Ca2+ elevations play a permissive role in these events, but th...

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Autores principales: Toledo, Flavia D., Pérez, Leonardo Martín, Basiglio, Cecilia Lorena, Ochoa, Justina E., Sánchez Pozzi, Enrique Juan, Roma, Marcelo Gabriel
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Springer 2018
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Acceso en línea:http://hdl.handle.net/2133/10485
http://hdl.handle.net/2133/10485
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