Protein arginine Methyltransferase 8 gene is expressed in pluripotent stem cells and its expression is modulated by the transcription factor Sox2
Addition of methyl groups to arginine residues is catalyzed by a group of enzymes called Protein Arginine Methyltransferases (Prmt). Although Prmt1 is essential in development, its paralogue Prmt8 has been poorly studied. This gene was reported to be expressed in nervous system and involved in neuro...
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| Otros Autores: | , , , , , , , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier B.V.
2016
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 14459caa a22017657a 4500 | ||
|---|---|---|---|
| 001 | PAPER-16053 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204655.0 | ||
| 008 | 190411s2016 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-84963647230 | |
| 024 | 7 | |2 cas |a protein arginine methyltransferase; Homeodomain Proteins; Nanog protein, mouse; Octamer Transcription Factor-3; Pou5f1 protein, mouse; PRMT8 protein, mouse; Protein-Arginine N-Methyltransferases; RNA, Small Interfering; Sox2 protein, mouse; SOXB1 Transcription Factors | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a BBRCA | ||
| 100 | 1 | |a Solari, C. | |
| 245 | 1 | 0 | |a Protein arginine Methyltransferase 8 gene is expressed in pluripotent stem cells and its expression is modulated by the transcription factor Sox2 |
| 260 | |b Elsevier B.V. |c 2016 | ||
| 270 | 1 | 0 | |m Guberman, A.; Laboratorio de Regulación Génica en Células Madre, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Guiraldes 2160, Argentina; email: algub@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
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| 504 | |a Najbauer, J., Johnson, B.A., Young, A.L., Aswad, D.W., Peptides with sequences similar to glycine, arginine-rich motifs in proteins interacting with RNA are efficiently recognized by methyltransferase(s) modifying arginine in numerous proteins (1993) J. Biol. Chem., 268, pp. 10501-10509 | ||
| 504 | |a Bedford, M.T., Richard, S., Arginine methylation an emerging regulator of protein function (2005) Mol. Cell, 18, pp. 263-272 | ||
| 504 | |a Bedford, M.T., Clarke, S.G., Protein arginine methylation in mammals: Who, what, and why (2009) Mol. Cell, 33, pp. 1-13 | ||
| 504 | |a Tang, J., Frankel, A., Cook, R.J., Kim, S., Paik, W.K., Williams, K.R., PRMT1 is the predominant type i protein arginine methyltransferase in mammalian cells (2000) J. Biol. Chem., 275, pp. 7723-7730 | ||
| 504 | |a Pawlak, M.R., Scherer, C.A., Chen, J., Roshon, M.J., Ruley, H.E., Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable (2000) Mol. Cell Biol., 20, pp. 4859-4869 | ||
| 504 | |a Lee, J., Sayegh, J., Daniel, J., Clarke, S., Bedford, M.T., PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family (2005) J. Biol. Chem., 280, pp. 32890-32896 | ||
| 504 | |a Kousaka, A., Mori, Y., Koyama, Y., Taneda, T., Miyata, S., Tohyama, M., The distribution and characterization of endogenous protein arginine N-methyltransferase 8 in mouse CNS (2009) Neuroscience, 163, pp. 1146-1157 | ||
| 504 | |a Zhang, X., Cheng, X., Structure of the predominant protein arginine methyltransferase PRMT1 and analysis of its binding to substrate peptides (2003) Structure, 11, pp. 509-520 | ||
| 504 | |a Li, H.-T., Gong, T., Zhou, Z., Liu, Y.-T., Cao, X., He, Y., Yeast Hmt1 catalyses asymmetric dimethylation of histone H3 arginine 2 in vitro (2015) Biochem. J., 467, pp. 507-515 | ||
| 504 | |a Lee, W.-C., Lin, W.-L., Matsui, T., Chen, E.S.-W., Wei, T.-Y.W., Lin, W.-H., Protein arginine methyltransferase 8: Tetrameric structure and protein substrate specificity (2015) Biochemistry | ||
| 504 | |a Toma-Fukai, S., Kim, J.-D., Park, K.-E., Kuwabara, N., Shimizu, N., Krayukuhina, E., Novel helical assembly in arginine methyltransferase 8 (2016) J. Mol. Biol. | ||
| 504 | |a Sayegh, J., Webb, K., Cheng, D., Bedford, M.T., Clarke, S.G., Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain (2007) J. Biol. Chem., 282, pp. 36444-36453 | ||
| 504 | |a Dillon, M.B.C., Rust, H.L., Thompson, P.R., Mowen, K.A., Automethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity (2013) J. Biol. Chem., 288, pp. 27872-27880 | ||
| 504 | |a Lin, Y., Tsai, Y.-J., Liu, Y.-F., Cheng, Y.-C., Hung, C.-M., Lee, Y.-J., The critical role of protein arginine methyltransferase prmt8 in zebrafish embryonic and neural development is non-redundant with its paralogue prmt1 (2013) PLoS One, 8, p. e55221 | ||
| 504 | |a Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Póliska, S., PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology (2015) Stem Cells, 33, pp. 726-741 | ||
| 504 | |a Losino, N., Luzzani, C., Solari, C., Boffi, J., Tisserand, M.L., Sevlever, G., Maintenance of murine embryonic stem cells' self-renewal and pluripotency with increase in proliferation rate by a bovine granulosa cell line-conditioned medium (2011) Stem Cells Dev., 20, pp. 1439-1449 | ||
| 504 | |a Luzzani, C., Solari, C., Losino, N., Ariel, W., Romorini, L., Bluguermann, C., Modulation of chromatin modifying factors' gene expression in embryonic and induced pluripotent stem cells (2011) Biochem. Biophys. Res. Commun., 410, pp. 816-822. , S0006-291X(11)01043-6 [pii] | ||
| 504 | |a Losino, N., Waisman, A., Solari, C., Luzzani, C., Espinosa, D.F., Sassone, A., EDA-containing fibronectin increases proliferation of embryonic stem cells (2013) PLoS One, 8. , e80681 | ||
| 504 | |a Solari, C., Vázquez Echegaray, C., Cosentino, M.S., Petrone, M.V., Waisman, A., Luzzani, C., Manganese superoxide dismutase gene expression is induced by nanog and oct4, essential pluripotent stem cells' transcription factors (2015) PLoS One, 10. , e0144336 | ||
| 504 | |a Ying, Q.-L., Stavridis, M., Griffiths, D., Li, M., Smith, A., (2003) Conversion of Embryonic Stem Cells into Neuroectodermal Precursors in Adherent Monoculture | ||
| 504 | |a Solari, C., Losino, N., Luzzani, C., Waisman, A., Bluguermann, C., Questa, M., Induced pluripotent stem cells' self-renewal and pluripotency is maintained by a bovine granulosa cell line-conditioned medium (2011) Biochem. Biophys. Res. Commun., 410, pp. 252-257. , S0006-291X(11)00901-6 [pii] | ||
| 504 | |a Di Rienzo, J.A., Casanoves, F., Balzarini, M.G., Gonzalez, L., Tablada, M., (2014) Infostat - Statistical Software, , Grupo InfoStat, FCA, Universidad Nacional de Córdoba Argentina | ||
| 504 | |a Kim, J., Chu, J., Shen, X., Wang, J., Orkin, S.H., An extended transcriptional network for pluripotency of embryonic stem cells (2008) Cell, 132, pp. 1049-1061 | ||
| 504 | |a Weng, M.K., Zimmer, B., Pöltl, D., Broeg, M.P., Ivanova, V., Gaspar, J.A., Extensive transcriptional regulation of chromatin modifiers during human neurodevelopment (2012) PLoS One, 7, p. e36708 | ||
| 504 | |a Weng, M.K., Natarajan, K., Scholz, D., Ivanova, V.N., Sachinidis, A., Hengstler, J.G., Lineage-specific regulation of epigenetic modifier genes in human liver and brain (2014) PLoS One, 9, p. e102035 | ||
| 504 | |a Hernandez, S., Dominko, T., Novel protein arginine methyltransferase 8 isoform is essential for cell proliferation (2016) J. Cell. Biochem. | ||
| 504 | |a Xie, W., Merz, G., Denman, R.B., PH uniquely modulates protein arginine methylation (2011) J. Biophys. Struct. Biol., 3, pp. 49-65 | ||
| 520 | 3 | |a Addition of methyl groups to arginine residues is catalyzed by a group of enzymes called Protein Arginine Methyltransferases (Prmt). Although Prmt1 is essential in development, its paralogue Prmt8 has been poorly studied. This gene was reported to be expressed in nervous system and involved in neurogenesis. In this work, we found that Prmt8 is expressed in mouse embryonic stem cells (ESC) and in induced pluripotent stem cells, and modulated along differentiation to neural precursor cells. We found that Prmt8 promoter activity is induced by the pluripotency transcription factors Oct4, Sox2 and Nanog. Moreover, endogenous Prmt8 mRNA levels were reduced in ESC transfected with Sox2 shRNA vector. As a whole, our results indicate that Prmt8 is expressed in pluripotent stem cells and its transcription is modulated by pluripotency transcription factors. These findings suggest that besides its known function in nervous system, Prmt8 could play a role in pluripotent stem cells. © 2016 Elsevier Inc. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica, PICT 2011-2713 | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, PIP112-201101-00243, PIP 112-200801-03003 | ||
| 536 | |a Detalles de la financiación: The authors wish to thank to Estefanía Rojas, Marcelo Schultz, Naomi Arakaki, Flavio S. de Souza, Emilly Villodre and Guido Lenz for their helpful assistance. This work was supported by the following grants (to A.G.): ANPCyT , PICT 2011-2713 , CONICET , PIP 112-200801-03003 and PIP112-201101-00243 . CS, MSC, AW and CL are fellows from CONICET. | ||
| 593 | |a Laboratorio de Regulación Génica en Células Madre, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Guiraldes 2160, Buenos Aires, C1428EGA, Argentina | ||
| 593 | |a Instituto de Química Biológica - Ciencias Exactas y Naturales (IQUIBICEN), UBA/CONICET, Buenos Aires, Argentina | ||
| 593 | |a Laboratorio de Investigación Aplicada A Las Neurociencias (LIAN)-CONICET, Fundación Para la Lucha Contra Las Enfermedades Neurológicas de la Infancia (FLENI), Buenos Aires, Argentina | ||
| 593 | |a Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina | ||
| 593 | |a Departamento de Fisiología y Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 593 | |a 4 Ruta 9 Km. 52.5, Escobar, Buenos Aires, B1625XAF, Argentina | ||
| 690 | 1 | 0 | |a EMBRYONIC STEM CELLS |
| 690 | 1 | 0 | |a INDUCED PLURIPOTENT STEM CELLS |
| 690 | 1 | 0 | |a NANOG |
| 690 | 1 | 0 | |a OCT4 |
| 690 | 1 | 0 | |a PRMT8 |
| 690 | 1 | 0 | |a SOX2 |
| 690 | 1 | 0 | |a MESSENGER RNA |
| 690 | 1 | 0 | |a OCTAMER TRANSCRIPTION FACTOR 4 |
| 690 | 1 | 0 | |a PROTEIN ARGININE METHYLTRANSFERASE |
| 690 | 1 | 0 | |a PROTEIN ARGININE METHYLTRANSFERASE 8 |
| 690 | 1 | 0 | |a SHORT HAIRPIN RNA |
| 690 | 1 | 0 | |a TRANSCRIPTION FACTOR NANOG |
| 690 | 1 | 0 | |a TRANSCRIPTION FACTOR SOX2 |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a HOMEODOMAIN PROTEIN |
| 690 | 1 | 0 | |a NANOG PROTEIN, MOUSE |
| 690 | 1 | 0 | |a OCTAMER TRANSCRIPTION FACTOR 4 |
| 690 | 1 | 0 | |a POU5F1 PROTEIN, MOUSE |
| 690 | 1 | 0 | |a PRMT8 PROTEIN, MOUSE |
| 690 | 1 | 0 | |a PROTEIN ARGININE METHYLTRANSFERASE |
| 690 | 1 | 0 | |a SMALL INTERFERING RNA |
| 690 | 1 | 0 | |a SOX2 PROTEIN, MOUSE |
| 690 | 1 | 0 | |a TRANSCRIPTION FACTOR SOX |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a BINDING SITE |
| 690 | 1 | 0 | |a CELL DIFFERENTIATION |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DOWN REGULATION |
| 690 | 1 | 0 | |a EMBRYO |
| 690 | 1 | 0 | |a GENE EXPRESSION |
| 690 | 1 | 0 | |a GENETIC TRANSFECTION |
| 690 | 1 | 0 | |a MOUSE |
| 690 | 1 | 0 | |a MOUSE EMBRYONIC STEM CELL |
| 690 | 1 | 0 | |a NEURAL STEM CELL |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a NUCLEAR REPROGRAMMING |
| 690 | 1 | 0 | |a PLURIPOTENT STEM CELL |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROMOTER REGION |
| 690 | 1 | 0 | |a UPREGULATION |
| 690 | 1 | 0 | |a 3T3 CELL LINE |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a CELL DIFFERENTIATION |
| 690 | 1 | 0 | |a CYTOLOGY |
| 690 | 1 | 0 | |a FIBROBLAST |
| 690 | 1 | 0 | |a GENE EXPRESSION REGULATION |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a NERVE CELL |
| 690 | 1 | 0 | |a PLURIPOTENT STEM CELL |
| 690 | 1 | 0 | |a REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a CELL DIFFERENTIATION |
| 690 | 1 | 0 | |a DOWN-REGULATION |
| 690 | 1 | 0 | |a FIBROBLASTS |
| 690 | 1 | 0 | |a GENE EXPRESSION REGULATION, ENZYMOLOGIC |
| 690 | 1 | 0 | |a HOMEODOMAIN PROTEINS |
| 690 | 1 | 0 | |a MICE |
| 690 | 1 | 0 | |a NEURONS |
| 690 | 1 | 0 | |a NIH 3T3 CELLS |
| 690 | 1 | 0 | |a OCTAMER TRANSCRIPTION FACTOR-3 |
| 690 | 1 | 0 | |a PLURIPOTENT STEM CELLS |
| 690 | 1 | 0 | |a PROMOTER REGIONS, GENETIC |
| 690 | 1 | 0 | |a PROTEIN-ARGININE N-METHYLTRANSFERASES |
| 690 | 1 | 0 | |a REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION |
| 690 | 1 | 0 | |a RNA, SMALL INTERFERING |
| 690 | 1 | 0 | |a SOXB1 TRANSCRIPTION FACTORS |
| 690 | 1 | 0 | |a TRANSFECTION |
| 700 | 1 | |a Echegaray, C.V. | |
| 700 | 1 | |a Luzzani, C. | |
| 700 | 1 | |a Cosentino, M.S. | |
| 700 | 1 | |a Waisman, A. | |
| 700 | 1 | |a Petrone, M.V. | |
| 700 | 1 | |a Francia, M. | |
| 700 | 1 | |a Sassone, A. | |
| 700 | 1 | |a Canizo, J. | |
| 700 | 1 | |a Sevlever, G. | |
| 700 | 1 | |a Barañao, L. | |
| 700 | 1 | |a Miriuka, S. | |
| 700 | 1 | |a Guberman, A. | |
| 773 | 0 | |d Elsevier B.V., 2016 |g v. 473 |h pp. 194-199 |k n. 1 |p Biochem. Biophys. Res. Commun. |x 0006291X |w (AR-BaUEN)CENRE-905 |t Biochemical and Biophysical Research Communications | |
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